CBMA

Centro de Biologia Molecular e Ambiental

Centre of Molecular and Environmental Biology

Bionanoparticles: challenges and therapeutic opportunities 

Dates & Venue
May 23 to 3 June
MICA Amphiteatre (room 2042), School of Sciences, Department of Biology, University of Minho, Campus de Gualtar

Syllabus
The development of nanodevices ever more complex for better efficacy in diagnostic and therapy is a new tool to boost conventional medicine. Concerns regarding the safety and potential exposure risks to nanoparticles have however been raised. 
The main topics in this course are:
-Global notions on nanoparticles, bionanotechnology and theranostics.
-Nanomaterials and formulations used in nanoparticle design for drug, siRNA and/or diagnostic marker delivery.
-Techniques for evaluating nanoparticle biocompatibility, bioavailability and toxicity.
-New drug nanodelivery systems for diagnosis and therapeutics of pathologies such as cancer, rheumatoid arthritis, as well as strategies based on nanotechnology to control and modulate immune responses.
-The potential risks of exposure by the human body to nanoparticles, particularly at the level of the immune system.
Learning outcomes
• To describe the concepts of nanoparticles, bionanotechnology and theranostics.
• To discern between the nanomaterials and formulations used in the design of new drug nanodelivery systems for diagnosis and therapeutics of diseases such as cancer, rheumatoid arthritis as well as modulation of immune responses.
• To list the techniques for evaluating nanoparticle biocompatibility, bioavailability and toxicity.
• To understand the main applications and limitations of such nanoparticles
• To explain the different techniques to study interaction nanoparticle – cell, since preparation to analysis of nanoparticle effects in exposed cell.
• The role fo the health professionals in the oncological patient care
• To develop capacities to analyze, criticize and communicate scientific results.

Teaching methodology
has a great focus on Seminars given by experts in their area (in-house and invited lecturers of prestigious repute). The students are asked to discuss relevant published articles and publically present their views. 
Laboratory classes where students will produce nanocarriers (e.g. liposomes) and use cancer research models namely cell lines for nanoparticles testing.

The student will be evaluated by a group presentation in which the results obtained during the practical classes will be critically analysed (30%) and by the presentation of a possible research project on a given research topic (70%).
IN-house lecturers
Ana Preto, CBMA, Department of Biology, University of Minho. 
Andreia Gomes, CBMA, Department of Biology, University of Minho.
Elisabete Oliveira, CFUM, Department of Physics, University of Minho.
Marlene Lúcio, CFUM, Department of Physics, University of Minho.
Ana Paula Sampaio CBMA, Department of Biology, University of Minho.
Ivo Lopes Nanodelivery - I&D em Bionanotecnologia Lda.
Joana Fernandes CBMA, Department of Biology, University of Minho.
Invited lecturers
Sofia A. Costa Lima, Requimte, Laboratório de Química Aplicada, Department of Chemistry, Faculty of Pharmacy, University of Porto
Andreia Marques Valente, Organic and Organometallic Chemistry Group, Faculty of Sciences, Lisbon University
Maria José Oliveira, I3S/INEB, University of Porto
Marisa Passos, INL - Laboratório Ibérico Internacional de Nanotecnologia
Ana Oliveira, Phyzat Biopharmaceuticals
Bruno Sarmento, I3S/INEB, University of Porto


  

 

 

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