Centro de Biologia Molecular e Ambiental

Centre of Molecular and Environmental Biology

Advanced course on plasma membrane transporters: physiology, genetics and phylogeny - 4th Edition

COORDINATOR Margarida Casal
CBMA-DB, Universidade do Minho
VENUE Departamento de Biologia, Universidade do Minho
4 –16 June


The control of solutes transport across biological membranes is a vital process for the homeostasis and long term stability of any cell, therefore unravelling the molecular mechanisms underlying the movement of solutes across biological membranes is an important focus of fundamental and applied research. Cells possess integral membrane proteins (IMP) that facilitate the movement of lipid-insoluble molecules which account for approximately one third of the coding capacity of the genes in an average organism. As they are critically important for multiple central functions in any living cell it is estimated that IMP provide 80 to 90% of the targets relevant for the chemical and pharmaceutical industries.
This course has been organized for post-graduation students or researchers who are dedicated to the broad field of the study of the transport of solutes of all kinds in any biological material. It will provide seminars and lectures on very diverse aspects of transport-dedicated research as well as laboratory classes and computer assisted sessions on diverse methodologies commonly used to study transport systems, their function, phylogeny and molecular structure.

LECTURERS André Goffeau University of Louvain-la-Neuf, Belgique
Peter Henderson University of Leeds, UK
George Diallinas University of Athens, Greece
François Chaumont University of Louvain-la-Neuf, Belgium
Fátima Baltazar ICVS-3B´s, U.Minho, Portugal
Sandra Paiva CBMA, Universidade do Minho, Portugal
Cândida Lucas CITAB, Universidade do Minho, Portugal
Maria João Sousa CBMA-DB, Universidade do Minho, Portugal
Margarida Casal (organizer) CBMA-DB, Universidade do Minho, Portugal


This course includes theoretical modules on the following topics:

  • Cellular transport mechanisms, kinetics and energetics;
  • Transport mechanisms characterisation, gene expression and regulation; 
  • Permeases, pumps and channels in bacteria, yeast, animal and plant cells; 
  • Biogenesis of transport proteins, trafficking of plasma membrane proteins along the endocytic pathway;
  • Structural-functional analysis of transporters; 
  • The role of transporters in resistance to multiple drugs and stress response; 
  • Phylogenetic classification of transporter proteins.
CONTACTS AND INFORMATIONS Margarida Casal ( This e-mail address is being protected from spambots. You need JavaScript enabled to view it )

Centro de Biologia Molecular e Ambiental
Departamento de Biologia, Universidade do Minho
Campus de Gualtar 4710-054 Braga
Phone +351 253 604317
Fax +351 253 678980
Full course (with lab classes): N/A € (students: N/A€)
Just lectures: N/A€ (students: N/A€)

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