Centro de Biologia Molecular e Ambiental

Centre of Molecular and Environmental Biology

Post-graduated Training Programme: 2010 Edition


May 3-14
Organizers: M. Côrte-Real, M.J. Sousa, S. Chaves, O. Coutinho, A. Preto, B. Johansson
Mammalian and Yeast as Complementary Cell Models in Programmed Cell Death
Muriel Priault, Nadine Camougrand, Stéphen Manon, Renault Thibaud

CNC, Medicine Faculty, University of Coimbra, PORTUGAL
Ana Cristina Rego

IPATIMUP, Pharmacy Fac., University of Porto, PORTUGAL
Helena Vasconcelos

Pharmacy Faculty, University of Porto, PORTUGAL
Lucília Saraiva

CBMA-DB, University of Minho, PORTUGAL
Manuela Côrte-Real, Maria João Sousa, Susana Chaves, Ana Preto, Olga Coutinho, Bjorn Johansson
Topics on this course:
  1. Programmed Cell Death processes versus necrosis
  2. Apoptosis
  3. Autophagy and mitophagy: from yeasts to mammalian cells
  4. Programmed necrosis
  5. The central role of mitochondria in the intrinsic apoptotic pathway
  6. Heterologous expression of mammalian apoptotic proteins in yeast
  7. Regulation of Programmed Cell Death in Cancer and its Pharmacological Modulation
  8. Features of Cell Death in Neurodegenerative Diseases
May 17-28
Organizers: R. Reis, C. Pais, J. Palha, P. Maciel, F. Rodrigues, P. Sampaio, D. Schuller
Methods of DNA Analysis: State of the Art
Microarray Core Facility (MAF), VU University Medical Center, NL
Bauke Ysltra

ICVS, School of Health Sciences, University of Minho
Fernando Rodrigues, Joana Palha

CBMA-DB, University of Minho, PORTUGAL
Paula Sampaio, Dorit Schuller
June 14-23
Organizers: A. Preto, A. Gomes
Nanotechnologies Applied to Theranostics: from Diagnosis to Disease Therapy
University of Vigo, Spain
Africa González-Fernández, Susana Magadan, Belén Díaz

Cochin Institute, University of Paris Descartes, France
Georges Bismuth

Alfama, Inc., Lisbon, Portugal
Gonçalo Bernardes

Synovo GmbH, Tübingen, Germany
Michael Burnet

“Aurel Vlaicu”, University of Arad, Romania
Florentina-Daniela Munteanu

Department of Textile Engineer, University of Minho, Portugal
Artur Cavaco-Paulo, Helena Ferreira

INEB, Porto, Portugal
Ana Paula Pêgo

Department of Physics, University of Minho
Elisabete Oliveira

Department of Toxicology, Fac. of Pharmacy, Univ. of Porto
Helena Carmo

CBMA-DB, University of Minho, Portugal
Ana Preto, Andreia Gomes
Topics on this course:
  1. Basic notions on nanoparticles, nanotechnology and theranostics.
  2. Diverse processes to obtain nanoparticles for biomedical purposes.
  3. Different nanomaterials and formulations used in nanoparticles, as vehicles for drugs and/or diagnostic markers.
  4. Techniques for evaluating biocompatibility, bioavailability and toxicity of nanoparticles.
  5. Application of nanoparticles in diagnosis and therapy of inflammatory diseases and cancer.
June 28-July 3
Organizers: M. Casal, C. Lucas, S. Paiva, M.J. Sousa, C. Ferreira, H. Gerós
Plasma Membrane Transporters: Physiology, Genetics and Phylogeny
Univ. of Louvain-la-Neuf, Belgium
Andre Goffeau, François Chaumont

Univ. of Leeds, UK
Peter Henderson

Univ. of Göteborg, Sweden
Markus Tamas

CBMA-DB, University of Minho, Portugal
Hernâni Gerós, Margarida Casal, Cândida Lucas, Maria João Sousa, Sandra Paiva
Topics on this course:
  1. Cellular transport mechanisms, kinetics and energetics
  2. Transport mechanisms characterisation, gene expression and regulation
  3. Carriers and channels in bacteria, yeast, animal and plant cells
  4. Biogenesis of transport proteins, trafficking of plasma membrane proteins along the endocytic pathway
  5. Structural-functional analysis of transporters
  6. The role of transporters in resistance to multiple drugs and stress response
  7. Phylogenetic classification of transporter proteins
July 12-23
Organizers: D. Schuller, R. Martins
Industrial Yeast Molecular Systems Biology
INRA, Sciences pour Oenologie, FRANCE
Sylvie Dequin

University of Florence, Italy
Duccio Cavalieri

TU Hamburg, Germany
An-Ping Zeng

Biocant, Portugal
Conceição Egas

CESAM, Univ. of Aveiro
Laura Carreto

LNEG, Lisbon
Vitor Lopes

ESB, Catholic University
César Ferreira

IBB-DEB, Univ. of Minho
António Vicente, José Teixeira

CBMA-DB, University of Minho, Portugal
Dorit Schuller, Rui Martins
Topics on this course:
  1. The whole genome sequence of the Saccharomyces cerevisiae wine yeast EC1118: a frame to address the molecular bases of wine yeast adaptation
  2. Metabolic engineering of wine yeasts: current issues and challenges
  3. Reconstructing signaling in yeast by time courses
  4. Understanding biology through pathway analysis
  5. Reconstruction and analysis of genome-scale metabolic networks
  6. Reconstruction and analysis of regulatory networks
  7. Sequencing technologies - the next generation
  8. High-throughput methodologies for comparative genomics and transcriptomics
  9. Genome and gene expression diversity of Saccharomyces cerevisiae isolated from wine biotopes
  10. Technometrics applications for monitoring and modeling biological processes
  11. Opportunities of specific bioanalitical techniques on high-throughput data aquisition: Mass Spectrometry
  12. Managing wine sensory quality: strategies & tools
  13. High cell density systems for continuous beer production - role of yeast adhesion and ageing
  14. High cell density reactors in Bioengineering
  15. Better yeast for better wine - Saccharomyces cerevisiae strains for winemaking
  16. Technometrics - Overcoming the hurdle of biological complexity
  17. Complex Systems at the Industry - Tools for analyzing, interpret, manage and control biological processes
July 14-23
Organizers: F. Cássio, C. Pascoal, S. Sahadevan, S. Duarte
Integrative Assessment of Aquatic Ecosystem Health

A - Ecotoxicology and Environmental Risk Assessment
Golder Associates Lda, Vancouver, Canada
Peter Chapman

University of Coimbra, Portugal
Rui Ribeiro

University of Porto, Portugal
Lúcia Guilhermino

New University of Lisboa, Portugal
Maria Helena Costa

University of Minho, Portugal
Pedro Santos
Topics on this course:
  1. Water Framework Directive priority and emerging substances: sources, transport and fates
  2. Experimental setup (microcosms and mesocosms; indoors and outdoors; endpoints)
  3. Model organisms and bioassays
  4. Biomarkers of environmental stress
  5. Omics as emerging technologies in environmental hazard assessment
  6. Experimental design and data treatment (dose response models; estimation of
  7. endpoints).
  8. Environmental risk assessment and management (case studies)
  9. Role of ecotoxicology in policy making
B - Assessment of Freshwater Ecosystem Condition
University of the Basque Country, Spain
Arturo Elosegi

University of Vigo, Spain
Isabel Pardo

ARH-Norte, University of Minho, Portugal
António Brito

University of Coimbra, Portugal
Manuel Graça, Maria João Feio

University of Trás os Montes, Portugal
Rui Cortes

University of Aveiro, Portugal
Salomé Almeida

University of Minho, Portugal
Ronaldo Sousa

Topics on this course:
  1. Major threats to aquatic biodiversity
  2. Bioindicators of disturbance and human impacts
  3. Functional indicators of ecosystem health
  4. Metrics for ecological quality assessment
  5. Designing and optimization of water quality monitoring programmes
  6. Intercalibration of assessment methods of river ecological status
  7. Water Framework Directive and other EU policies for water use and management
  8. Current status of the river basin management plans in Iberian and European rivers
  9. River restoration
  10. Practicals: field trip, sampling techniques, training on identification, data analysis and ecological interpretation.

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